Cancer Prevention Clinical Trials

Listed below are clinical trials related to cancer prevention. If you are interested in learning more about a trial, access the Web site address or call the phone number provided for additional information.

Breast
Genistein in Preventing Breast Cancer in Women at High Risk for Breast Cancer
View site

Exemestane in Preventing Cancer in Postmenopausal Women at Increased Risk of Developing Breast Cancer
View site

Green Tea Extract in Treating Women With Hormone Receptor-Negative Stage I, Stage II, or Stage IIIA Breast Cancer
View site

IBIS-II (International Breast Cancer Intervention Study) is an international, multicenter study of anastrozole versus placebo in 6,000 postmenopausal women at increased risk of breast cancer (a separate part of the study will evaluate anastrozole versus tamoxifen in postmenopausal women with ductal carcinoma in situ).
View site

SPORE Trial is a phase II randomized pilot study of letrozole in preventing breast cancer in postmenopausal women who are at increased risk due to elevated estradiol levels
View site

Phase I Pilot Chemoprevention Study of IH636 Grape Seed Proanthocyanidin Extract in Healthy Postmenopausal Women at High Risk of Developing Breast Cancer
View site

Phase II Study of Deslorelin Combined With Low-Dose Add-Back Estradiol and Testosterone in Preventing Breast Cancer in Premenopausal Women Who Are at High Risk for This Disease
View site

Phase II Randomized Chemoprevention Study of Tamoxifen in Women at Increased Risk for Breast Cancer
View site

Pilot Randomized Study of Physical Activity Intervention in Sedentary Women With a History of Breast Cancer or at High Risk for Breast Cancer
View site

Anastrozole in Preventing Breast Cancer in Postmenopausal Women at Increased Risk of Breast Cancer
View site

Raloxifene and Goserelin in Preventing Breast Cancer in Women With a Family History of Breast Cancer
View site

Comprehensive Screening for Women at High Genetic Risk for Developing Breast Cancer
View site

Breast Study Investigating a New Light Technique to Monitor Changes in Breast Tissue Density
View site

READ Trial: Radiologic Evaluation and Breast Density (READ) Radiologic Evaluation and Breast Density
View site

Randomized Study of Computer-Aided Breast Cancer Detection in Women Undergoing Screening Mammography
View site

Randomized Study of The Mammography FastTrack Program for Improving Rates of Breast Cancer Screening in Women
View site

Randomized Study of the Effect of Acetylsalicylic Acid Versus Placebo on Mammogram Density in Healthy Postmenopausal Women With Moderate- to High-Level of Breast Density
View site

Sister Study
View site

Soy Isoflavones and Breast Cancer Risk Reduction
View site

Soy Protein and Breast Cancer Risk Reduction
View site

Phase II Randomized Study of Celecoxib in Premenopausal Women at High Risk for Developing Breast CancerPhase II Randomized Study of Celecoxib in Premenopausal Women at High Risk for Developing Breast Cancer
View site

Gastrointestinal
Vitamin D/Calcium Polyp Prevention Study
View site

Green Tea Extract in Preventing Esophageal Cancer in Patients With Barrett's Esophagus
View site

Curcumin for the Chemoprevention of Colorectal Cancer
View site

Celecoxib in Preventing Colorectal Cancer in Young Patients With a Genetic Predisposition for Familial Adenomatous Polyposis
View site

Community-Based H. Pylori Eradication
View site

Esomeprazole With or Without Aspirin in Preventing Esophageal Cancer in Patients With Barrett's Metaplasia
View site

Phase I Randomized Study of Folate-Depleted Versus Folate-Supplemented Diet for the Prevention of Colorectal Cancer in Patients at High Risk for Colorectal Neoplasia
View site

Phase II Randomized Study of Celecoxib With or Without Eflornithine For the Prevention of Colorectal Cancer in Participants With Familial Adenomatous Polyposis of the Colorectum (sponsored by the MD Anderson Cancer Center and the NCI)
View site

Phase III Randomized Screening Study of Colonoscopy Versus Annual Fecal Occult Blood Test in Healthy Participants at Average Risk for Colorectal Cancer
View site

Phase III Randomized Study of Celecoxib in Genotype-Positive Pediatric Patients With Familial Adenomatous Polyposis
View site

Vitamin D/Calcium Polyp Prevention Study
View site

Use of Curcumin in the Lower Gastrointestinal Tract in Familial Adenomatous Polyposis Patients
View site

Phase I Randomized Study of Nitric Oxide-Releasing Acetylsalicyclic Acid in Patients at High Risk for Colorectal Cancer
View site

Phase II Randomized Chemoprevention Study of Acetylsalicylic Acid (Aspirin) in Patients at Increased Risk for the Development or Recurrence of Colorectal Cancer
View site

Randomized Study of Traditional Print Versus Simple Electronic Communication Versus Usual Care to Improve Colorectal Cancer Screening Compliance in Older Women
View site

Community-Based H. Pylori Eradication
View site

Feasibility Study of Phototherapy System to Treat H Pylori
View site

Gynecologic
Human Papillomavirus (HPV) Vaccine Consistency and Non-Inferiority Trial in Young Adult Women
View site

Phase II Randomized Study of Medroxyprogesterone Versus Ethinyl Estradiol and Norgestrel For the Prevention of Endometrial Carcinogenesis in Women With a Known Hereditary Non-Polyposis Colon Cancer (HNPCC)-Associated Gene Mutation or HNPCC-Associated Cancer(s)
View site

Phase II Study of Celecoxib in Treating Patients With Cervical Intraepithelial Neoplasia
View site

Study of Individuals and Families at High Risk for Breast or Ovarian Cancer
View site

Ovarian Screening Study
View site

Ovarian Cancer Early Detection Program: Screening and Genetic Study
View site

Head and Neck
A Phase II Trial to Assess the Effects of Green Tea in Oral Leukoplakia
View site

Erlotinib Prevention of Oral Cancer (EPOC)
View site

Phase I/II Study of Oral and Intramucosal Ad5CMV-p53 Gene in Patients With Diffuse Premalignant Carcinoma of the Oral Cavity or Oral Pharynx
View site

Phase II Randomized Chemoprevention Study of Bowman-Birk Inhibitor Concentrate in Patients With Oral Leukoplakia
View site

Phase II Chemoprevention Study of Pioglitazone in Patients With Hyperplastic or Dysplastic Oral Cavity or Oropharyngeal Leukoplakia
View site

Phase I/II Study of Chemoprevention With EGFR and COX-2 Inhibitor in Premalignant Lesions of Head and Neck of Former Smokers
View site

A Pilot Multi-Center International Double-Blind Placebo Ccontrolled Randomized Study of Sulindac, a Pan-Cox Inhibitor,in Oral Premalignant Lesions
View site

Hematologic
Prospective Study of Clinical, Laboratory, Genetic, and Epidemiological Characterization of Individuals and Families at High Risk for Hematological Cancer
View site

Lung
Phase II Randomized Pilot Chemoprevention Study of Celecoxib in Former Heavy Smokers At High Risk of Primary or Second Primary Lung Cancer (sponsored by the Jonsson Comprehensive Cancer Center and the NCI)
View site

Phase III Study of Selenium in Preventing Tumor Growth in Patients With Previously Resected Stage I Non-small Cell Lung Cancer
View site

Phase II Randomized Chemoprevention Study of Iloprost in Patients at High Risk for Lung Cancer
View site

LIFE Trial: Lung Bronchoscopy in Patients at Risk for Developing Lung Cancer
View site

Phase II Randomized Study of Green Tea or Polyphenon E in Preventing Lung Cancer in Former Smokers With Chronic Obstructive Pulmonary Disease
View site

Chemoprevention Study of Broccoli Sprout Extract in Smokers
View site

Phase II Randomized Chemoprevention Study of Inhaled Budesonide in Patients With Lung Nodules at High Risk of Developing Lung Cancer
View site

Randomized Study of Motivational Counseling in Preventing Postpartum Smoking Relapse in Pregnant Women Who Quit Smoking During Pregnancy
View site

Prostate
IMPACT Study: Identification of Men With a Genetic Predisposition to ProstAte Cancer
View site

Shared Decision Making: Prostate Cancer Screening
View site

Community Interventions in Non-Medical Settings to Increase Informed Decision Making for Prostate Cancer Screening
View site

Phase II Study of Prostate Cancer Screening and Dietary Heterocyclic Amine Exposure in African American Men
View site

Randomized Study of Fish Oil Supplements in Preventing Prostate Cancer in Patients With Prostatic Intraepithelial Neoplasia or Who Are at Risk for Developing Prostate Cancer
View site

Effects of ASA on Prostate Tissue
View site

Phase I Randomized Study of Lycopene in Healthy Male Participants
View site

Phase II Randomized Chemoprevention Study of Calcitriol in Patients With High-Grade Prostatic Intraepithelial Neoplasia
View site

Skin
Phase II Randomized Study of Celecoxib as a Chemopreventive Agent Inhibiting UV-Induced Erythema and Biomarkers of Cutaneous Carcinogenesis Participants With FitzpatrickType I-IV Skin (sponsored by the Herbert J. Irving Cancer Center and the NCI)
View site

Study of Clinical, Laboratory, and Epidemiologic Characteristics of Individuals and Families at High Risk for Melanoma
View site

Screening Study of Cancer Risk in Participants Who are Heterozygous Carriers of Xeroderma Pigmentosum Disease Gene Mutations Versus Non-Carrier Blood Relatives or Spouses
View site

Sun Protection for Florida's Children
View site