Listed below are clinical trials related to cancer prevention. If you are interested in learning more about a trial, access the Web site address or call the phone number provided for additional information.
Prevention
Lung
Phase II Randomized Pilot Chemoprevention Study of Celecoxib in Former Heavy Smokers At High Risk of Primary or Second Primary Lung Cancer (sponsored by the Jonsson Comprehensive Cancer Center and the NCI)
View site
Phase I Study of Inositol for the Prevention of Lung Cancer in Patients With Bronchial Epithelial Dysplasia Who Are Current or Former Smokers (sponsored by the British Columbia Cancer Agency and the NCI)
View site
Phase II Study of Zileuton for the Prevention of Lung Cancer in Patients With Bronchial Dysplasia (sponsored by the Barbara Ann Karmanos Cancer Institute and the NCI)
View site
Phase III Study of Selenium in Preventing Tumor Growth in Patients With Previously Resected Stage I Non-small Cell Lung Cancer
View site
Phase II Chemoprevention Study of Iloprost in Patients at High Risk for Lung Cancer
View site
Breast
IBIS-II (International Breast Cancer Intervention Study) is an international, multicenter study of anastrozole versus placebo in 6,000 postmenopausal women at increased risk of breast cancer (a separate part of the study will evaluate anastrozole versus tamoxifen in postmenopausal women with ductal carcinoma in situ).
View site
Phase II Chemoprevention Study of Celecoxib in Premenopausal Women at High Risk For Estrogen Receptor-Negative Breast Cancer (sponsored by the University of Kansas and the NCI)
View site
Randomized Chemoprevention Study of Bexarotene in Women at High Genetic Risk for Breast Cancer (sponsored by the Baylor College of Medicine and the NCI)
View site
Pilot Randomized Study of Raloxifene and Goserelin Versus No Medical Intervention in Women at High Genetic Risk for Developing Breast Cancer (sponsored by the National Cancer Research Institute)
View site
Phase II Chemoprevention Study of Celecoxib in Premenopausal Women at High Risk For Estrogen Receptor-Negative Breast Cancer
View site
Phase II Randomized Study of Polyphenon E (Green Tea Extract) and Low-Dose Aspirin in Women at High Risk For Developing Breast Cancer
View site
Randomized Study of Exemestane for the Reduction of Breast Density in Postmenopausal Women at Increased Risk for Breast Cancer
View site
Phase III Study of Exemestane With or Without Celecoxib in Preventing Cancer in Postmenopausal Women at Increased Risk of Developing Breast Cancer
View site
Phase II Study of Exemestane Alone or Combined With Celecoxib in Treating Postmenopausal Women at High Risk for Invasive Breast Cancer
View site
Phase II Study of Macrobiotic Diet and Flax Seed: Effects on Estrogens, Phytoestrogens, & Fibrinolytic Factors
View site
Phase II Study of Deslorelin Combined With Low-Dose Add-Back Estradiol and Testosterone in Preventing Breast Cancer in Premenopausal Women Who Are at High Risk for This Disease
View site
Phase II Study of Ductal Lavage in Assessing Women With Early Breast Cancer or at High Risk of Developing Breast Cancer Who Are Eligible For Tamoxifen Therapy
View site
Phase II Study of Celecoxib in Preventing Breast Cancer in At-Risk Premenopausal Women
View site
Phase I Study of the Effect of Tamoxifen on Breast Density in Premenopausal Women With Breast Cancer or High Risk for Breast Cancer
View site
Anastrozole in Preventing Breast Cancer in Postmenopausal Women at Increased Risk of Breast Cancer
View site
Bexarotene in Preventing Breast Cancer in Women at Genetic Risk
View site
Raloxifene and Goserelin in Preventing Breast Cancer in Women With a Family History of Breast Cancer
View site
Prostate
Phase I Study of Lycopene for the Chemoprevention of Prostate Cancer (sponsored by the University of Illinois and the NCI)
View site
Phase IIB Randomized Chemoprevention Study of Eflornithine (DFMO) in Patients at High Genetic Risk For Prostate Cancer
View site
Phase II Randomized Study of Dietary Soy in Patients With Elevated PSA Levels (sponsored by the Cancer and Leukemia Group B [CALGB] and the NCI)
View site
Phase II Randomized Prevention Study of Fat- and/or Flaxseed-Modified Diets in Patients With Newly Diagnosed Prostate Cancer
View site
Phase II Randomized Study of the Effects of a Low Fat, High Fiber Diet on Serum Factors in Patients With Prostate Cancer
View site
Phase III Randomized Study of Selenium as Chemoprevention of Prostate Cancer in Patients With High-Grade Prostatic Intraepithelial Neoplasia
View site
Phase II Chemoprevention Study of an Investigational Drug in Men with High Grade Prostate Intraepithelial Neoplasia (PIN)
View site
Randomized Study of Isoflavones in Reducing Risk Factors in Patients With Stage I or II Prostate Cancer
View site
Gastrointestinal
Phase II Randomized Study of Celecoxib With or Without Eflornithine For the Prevention of Colorectal Cancer in Participants With Familial Adenomatous Polyposis of the Colorectum (sponsored by the MD Anderson Cancer Center and the NCI)
View site
Phase II Randomized Chemoprevention Study of Celecoxib in Patients With Premalignant Rectal Polyps or Prior Sporadic Colorectal Neoplasia
View site
Phase II Randomized Study of Sulindac Versus Aspirin Versus Ursodiol for the Prevention of Colorectal Cancer in Patients With Aberrant Crypt Foci and a History of Colorectal Carcinoma or Adenoma
View site
Phase III Study of Celecoxib and/or Selenium in Treating Patients With Adenomatous Colorectal Polyps
View site
Phase III Study of Celecoxib in Preventing Polyps in Patients Who Have Undergone Surgery for Stage I Colon Cancer
View site
Phase II Study of Chemoprevention with Folic Acid
View site
Gynecologic
Randomized Study of Fenretinide as Chemoprevention in Patients at Increased Risk for Ovarian Cancer (sponsored by the Gynecologic Oncology Group [GOG] and the NCI)
View site
Phase II Study of Celecoxib in Preventing Cancer in Patients at High Risk for Ovarian Epithelial Cancer Who Are Undergoing Prophylactic Oophorectomy
View site
Phase II Randomized Study of Medroxyprogesterone Versus Ethinyl Estradiol and Norgestrel For the Prevention of Endometrial Carcinogenesis in Women With a Known Hereditary Non-Polyposis Colon Cancer-Associated Gene Mutation
View site
Phase II Study of Celecoxib in Treating Patients With High-Grade Squamous Intraepithelial Lesions of the Cervix
View site
Phase II Study of Celecoxib in Treating Patients With Cervical Intraepithelial Neoplasia
View site
Phase II Study of SGN-00101 in Treating Patients With Cervical Intraepithelial Neoplasia
View site
Phase II Study of SGN-00101 Immunotherapy in Treating Patients With Grade III Cervical Intraepithelial Neoplasia
View site
Phase II Randomized Study of SGN-00101 in Patients With Grade II or III Cervical Intraepithelial Neoplasia
View site
Skin
Phase II Randomized Study of Celecoxib for Chemoprevention of Basal Cell Carcinoma in Patients With Basal Cell Nevus Syndrome
View site
Phase II Randomized Study of Celecoxib as a Chemopreventive Agent Inhibiting UV-Induced Erythema and Biomarkers of Cutaneous Carcinogenesis Participants With FitzpatrickType I-IV Skin (sponsored by the Herbert J. Irving Cancer Center and the NCI)
View site
Phase II/III Randomized Chemoprevention Study of Celecoxib in Patients With Actinic Keratoses
View site
Hematologic
Phase II Randomized Chemoprevention Study of Dehydroepiandrosterone (DHEA) Versus Clarithromycin in Patients With Monoclonal Gammopathy of Undetermined or Borderline Significance (sponsored by the Mayo Clinic Cancer Center and the NCI)
View site
Bladder
Phase IIB/III Randomized Chemoprevention Study of Celecoxib in Patients With Superficial Transitional Cell Carcinoma of the Bladder at High Risk for Recurrence
View site
Oral
Phase II Pilot Study of Celecoxib as Chemoprevention of Head and Neck Squamous Cell Cancer in Patients With Oral Leukoplakia and/or Dysplasia
View site
Phase I/II Study of Oral and Intramucosal Ad5CMV-p53 Gene in Patients With Diffuse Premalignant Carcinoma of the Oral Cavity or Oral Pharynx
View site
Screening/Detection
Breast
Pilot Screening Study of Breast Imaging Outcome Measures in Women At High Genetic Risk of Breast Cancer
View site
Screening Study of Breast Imaging Outcome Measures and Phase of Menstrual Cycle in Women At High Genetic Risk of Breast Cancer
View site
Study of Individuals and Families at High Risk for Breast or Ovarian Cancer
View site
Screening Study of Breast Ultrasound and Mammography in Women at High Risk for Breast Cancer
View site
Sister Study
View site
Nipple Aspiration, Ductal Lavage, and Duct Endoscopy in Screening Women at Moderate-to-High Risk of Developing Breast Cancer
View site
Gastrointestinal
Randomized Screening Study of Fecal Occult Blood Testing and Multitarget DNA-Based Assay Panel Testing Followed By Colonoscopy in the Detection of Colorectal Cancer
View site
Low Literacy Intervention for Colorectal Cancer Screening
View site
Genetic and Environmental Risk Assessment for Colorectal Cancer in Healthy Participants
View site
Gynecologic
Study of Clinical, Genetic, Behavioral, Laboratory, and Epidemiologic Characteristics of Individuals and Families at High Risk of Breast or Ovarian Cancer
View site
National Ovarian Cancer Early Detection Program: Screening and Genetic Study is sponsored by the NCI and seeks to identify women at high risk of developing ovarian cancer as well as to identify and develop very sensitive and specific tumor markers for the detection of early stage disease. Six thousand women will be entered into the study. For more information, call the NCI at 1-800-4-CANCER.
View site
Randomized Screening Study of CA 125 and Ultrasound in the Detection of Ovarian Cancer in Postmenopausal Women
View site
Screening Study for Ovarian Cancer in Women Who are at High Genetic Risk for Developing Ovarian Cancer
View site
Prospective Screening Study of Risk-Reducing Salpingo-oophorectomy and Longitudinal CA 125 Screening in Participants at Increased Genetic Risk of Ovarian Cancer (sponsored by the GOG and the NCI)
View site
Study of Individuals and Families at High Risk for Breast or Ovarian Cancer
View site
Skin
Study of Clinical, Laboratory, and Epidemiologic Characteristics of Individuals and Families at High Risk for Melanoma
View site
Screening Study of Cancer Risk in Participants Who are Heterozygous Carriers of Xeroderma Pigmentosum Disease Gene Mutations Versus Non-Carrier Blood Relatives or Spouses
View site
Hematologic
Prospective Study of Clinical, Laboratory, Genetic, and Epidemiological Characterization of Individuals and Families at High Risk for Hematological Cancer
View site
