Prevention
Lung
Phase II Randomized Study of Zileuton for the Prevention of Lung Cancer in Patients With Bronchial Dysplasia
View sitePhase II Randomized Pilot Chemoprevention Study of Celecoxib in Former Heavy Smokers At High Risk of Primary or Second Primary Lung Cancer (sponsored by the Jonsson Comprehensive Cancer Center and the NCI)
View sitePhase III Study of Selenium in Preventing Tumor Growth in Patients With Previously Resected Stage I Non-small Cell Lung Cancer
View sitePhase II Chemoprevention Study of Iloprost in Patients at High Risk for Lung Cancer
View siteBreast
IBIS-II (International Breast Cancer Intervention Study) is an international, multicenter study of anastrozole versus placebo in 6,000 postmenopausal women at increased risk of breast cancer (a separate part of the study will evaluate anastrozole versus tamoxifen in postmenopausal women with ductal carcinoma in situ).
View siteSPORE Trial is a phase II randomized pilot study of letrozole in preventing breast cancer in postmenopausal women who are at increased risk due to elevated estradiol levels
View sitePhase I Pilot Chemoprevention Study of IH636 Grape Seed Proanthocyanidin Extract in Healthy Postmenopausal Women at High Risk of Developing Breast Cancer
View sitePhase II Study of Deslorelin Combined With Low-Dose Add-Back Estradiol and Testosterone in Preventing Breast Cancer in Premenopausal Women Who Are at High Risk for This Disease
View sitePhase II Randomized Chemoprevention Study of Tamoxifen in Women at Increased Risk for Breast Cancer
View sitePilot Randomized Study of Raloxifene and Goserelin Versus No Medical Intervention in Women at High Genetic Risk for Developing Breast Cancer (sponsored by the National Cancer Research Institute)
View sitePilot Randomized Study of Physical Activity Intervention in Sedentary Women With a History of Breast Cancer or at High Risk for Breast Cancer
View siteRandomized Chemoprevention Study of Bexarotene in Women at High Genetic Risk for Breast Cancer (sponsored by the Baylor College of Medicine and the NCI)
View siteRandomized Study of Exemestane for the Reduction of Breast Density in Postmenopausal Women at Increased Risk for Breast Cancer
View siteAnastrozole in Preventing Breast Cancer in Postmenopausal Women at Increased Risk of Breast Cancer
View siteRaloxifene and Goserelin in Preventing Breast Cancer in Women With a Family History of Breast Cancer
View siteProstate
Phase II Randomized Study of Dietary Soy in Patients With Elevated PSA Levels (sponsored by the Cancer and Leukemia Group B [CALGB] and the NCI)
View sitePhase III Randomized Study of Selenium as Chemoprevention of Prostate Cancer in Patients With High-Grade Prostatic Intraepithelial Neoplasia
View siteRandomized Study of Isoflavones in Reducing Risk Factors in Patients With Stage I or II Prostate Cancer
View siteGastrointestinal
Phase I Randomized Study of Folate-Depleted Versus Folate-Supplemented Diet for the Prevention of Colorectal Cancer in Patients at High Risk for Colorectal Neoplasia
View sitePhase II Randomized Study of Celecoxib With or Without Eflornithine For the Prevention of Colorectal Cancer in Participants With Familial Adenomatous Polyposis of the Colorectum (sponsored by the MD Anderson Cancer Center and the NCI)
View siteGynecologic
Phase II Randomized Study of Medroxyprogesterone Versus Ethinyl Estradiol and Norgestrel For the Prevention of Endometrial Carcinogenesis in Women With a Known Hereditary Non-Polyposis Colon Cancer (HNPCC)-Associated Gene Mutation or HNPCC-Associated Cancer(s)
View siteRandomized Study of Fenretinide as Chemoprevention in Patients at Increased Risk for Ovarian Cancer (sponsored by the Gynecologic Oncology Group [GOG] and the NCI)
View siteRandomized Chemoprevention Study of Fenretinide in Participants at High Risk for Ovarian Cancer Planning to Undergo Bilateral Oophorectomy
View sitePhase II Study of Celecoxib in Treating Patients With Cervical Intraepithelial Neoplasia
View siteSkin
Phase II Randomized Study of Celecoxib as a Chemopreventive Agent Inhibiting UV-Induced Erythema and Biomarkers of Cutaneous Carcinogenesis Participants With FitzpatrickType I-IV Skin (sponsored by the Herbert J. Irving Cancer Center and the NCI)
View siteOral
Phase I/II Study of Oral and Intramucosal Ad5CMV-p53 Gene in Patients With Diffuse Premalignant Carcinoma of the Oral Cavity or Oral Pharynx
View siteScreening/Detection
Breast
Pilot Screening Study of Breast Imaging Outcome Measures in Women At High Genetic Risk of Breast Cancer
View siteSister Study
View siteGastrointestinal
Low Literacy Intervention for Colorectal Cancer Screening
View sitePhase III Randomized Screening Study of Colonoscopy Versus Annual Fecal Occult Blood Test in Healthy Participants at Average Risk for Colorectal Cancer
View siteGynecologic
National Ovarian Cancer Early Detection Program: Screening and Genetic Study is sponsored by the NCI and seeks to identify women at high risk of developing ovarian cancer as well as to identify and develop very sensitive and specific tumor markers for the detection of early stage disease. Six thousand women will be entered into the study. For more information, call the NCI at 1-800-4-CANCER.
View siteStudy of Individuals and Families at High Risk for Breast or Ovarian Cancer
View siteSkin
Screening Study of Cancer Risk in Participants Who are Heterozygous Carriers of Xeroderma Pigmentosum Disease Gene Mutations Versus Non-Carrier Blood Relatives or Spouses
View siteHematologic
Prospective Study of Clinical, Laboratory, Genetic, and Epidemiological Characterization of Individuals and Families at High Risk for Hematological Cancer
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