Breast
IBIS-II (International Breast Cancer Intervention Study) is an international, multicenter study of anastrozole versus placebo in 6,000 postmenopausal women at increased risk of breast cancer (a separate part of the study will evaluate anastrozole versus tamoxifen in postmenopausal women with ductal carcinoma in situ).
SPORE Trial is a phase II randomized pilot study of letrozole in preventing breast cancer in postmenopausal women who are at increased risk due to elevated estradiol levels
Phase I Pilot Chemoprevention Study of IH636 Grape Seed Proanthocyanidin Extract in Healthy Postmenopausal Women at High Risk of Developing Breast Cancer
Phase II Study of Deslorelin Combined With Low-Dose Add-Back Estradiol and Testosterone in Preventing Breast Cancer in Premenopausal Women Who Are at High Risk for This Disease
Phase II Randomized Chemoprevention Study of Tamoxifen in Women at Increased Risk for Breast Cancer
Pilot Randomized Study of Physical Activity Intervention in Sedentary Women With a History of Breast Cancer or at High Risk for Breast Cancer
Anastrozole in Preventing Breast Cancer in Postmenopausal Women at Increased Risk of Breast Cancer
Raloxifene and Goserelin in Preventing Breast Cancer in Women With a Family History of Breast Cancer
Comprehensive Screening for Women at High Genetic Risk for Developing Breast Cancer
Breast Study Investigating a New Light Technique to Monitor Changes in Breast Tissue Density
READ Trial: Radiologic Evaluation and Breast Density (READ) Radiologic Evaluation and Breast Density
Randomized Study of Computer-Aided Breast Cancer Detection in Women Undergoing Screening Mammography
Randomized Study of The Mammography FastTrack Program for Improving Rates of Breast Cancer Screening in Women
Randomized Study of the Effect of Acetylsalicylic Acid Versus Placebo on Mammogram Density in Healthy Postmenopausal Women With Moderate- to High-Level of Breast Density
Sister Study
Soy Isoflavones and Breast Cancer Risk Reduction
Soy Protein and Breast Cancer Risk Reduction
Phase II Randomized Study of Celecoxib in Premenopausal Women at High Risk for Developing Breast CancerPhase II Randomized Study of Celecoxib in Premenopausal Women at High Risk for Developing Breast Cancer
Gastrointestinal
Esomeprazole With or Without Aspirin in Preventing Esophageal Cancer in Patients With Barrett's Metaplasia
Phase I Randomized Study of Folate-Depleted Versus Folate-Supplemented Diet for the Prevention of Colorectal Cancer in Patients at High Risk for Colorectal Neoplasia
Phase II Randomized Study of Celecoxib With or Without Eflornithine For the Prevention of Colorectal Cancer in Participants With Familial Adenomatous Polyposis of the Colorectum (sponsored by the MD Anderson Cancer Center and the NCI)
Phase III Randomized Screening Study of Colonoscopy Versus Annual Fecal Occult Blood Test in Healthy Participants at Average Risk for Colorectal Cancer
Phase III Randomized Study of Celecoxib in Genotype-Positive Pediatric Patients With Familial Adenomatous Polyposis
Vitamin D/Calcium Polyp Prevention Study
Use of Curcumin in the Lower Gastrointestinal Tract in Familial Adenomatous Polyposis Patients
Phase I Randomized Study of Nitric Oxide-Releasing Acetylsalicyclic Acid in Patients at High Risk for Colorectal Cancer
Phase II Randomized Chemoprevention Study of Acetylsalicylic Acid (Aspirin) in Patients at Increased Risk for the Development or Recurrence of Colorectal Cancer
Randomized Study of Traditional Print Versus Simple Electronic Communication Versus Usual Care to Improve Colorectal Cancer Screening Compliance in Older Women
Community-Based H. Pylori Eradication
Feasibility Study of Phototherapy System to Treat H Pylori
Gynecologic
Phase II Randomized Study of Medroxyprogesterone Versus Ethinyl Estradiol and Norgestrel For the Prevention of Endometrial Carcinogenesis in Women With a Known Hereditary Non-Polyposis Colon Cancer (HNPCC)-Associated Gene Mutation or HNPCC-Associated Cancer(s)
Phase II Study of Celecoxib in Treating Patients With Cervical Intraepithelial Neoplasia
Study of Individuals and Families at High Risk for Breast or Ovarian Cancer
Ovarian Screening Study
Ovarian Cancer Early Detection Program: Screening and Genetic Study
Head and Neck
Phase I/II Study of Oral and Intramucosal Ad5CMV-p53 Gene in Patients With Diffuse Premalignant Carcinoma of the Oral Cavity or Oral Pharynx
Phase II Randomized Chemoprevention Study of Bowman-Birk Inhibitor Concentrate in Patients With Oral Leukoplakia
Phase II Chemoprevention Study of Pioglitazone in Patients With Hyperplastic or Dysplastic Oral Cavity or Oropharyngeal Leukoplakia
Phase I/II Study of Chemoprevention With EGFR and COX-2 Inhibitor in Premalignant Lesions of Head and Neck of Former Smokers
Phase II Chemoprevention Study of Rosiglitazone in Patients With High-Risk Hyperplastic or Dysplastic Oral Leukoplakia
A Pilot Multi-Center International Double-Blind Placebo Ccontrolled Randomized Study of Sulindac, a Pan-Cox Inhibitor,in Oral Premalignant Lesions
Hematologic
Prospective Study of Clinical, Laboratory, Genetic, and Epidemiological Characterization of Individuals and Families at High Risk for Hematological Cancer
Lung
Phase II Randomized Pilot Chemoprevention Study of Celecoxib in Former Heavy Smokers At High Risk of Primary or Second Primary Lung Cancer (sponsored by the Jonsson Comprehensive Cancer Center and the NCI)
Phase III Study of Selenium in Preventing Tumor Growth in Patients With Previously Resected Stage I Non-small Cell Lung Cancer
Phase II Randomized Chemoprevention Study of Iloprost in Patients at High Risk for Lung Cancer
LIFE Trial: Lung Bronchoscopy in Patients at Risk for Developing Lung Cancer
Phase II Randomized Study of Green Tea or Polyphenon E in Preventing Lung Cancer in Former Smokers With Chronic Obstructive Pulmonary Disease
Chemoprevention Study of Broccoli Sprout Extract in Smokers
Phase II Randomized Chemoprevention Study of Inhaled Budesonide in Patients With Lung Nodules at High Risk of Developing Lung Cancer
Randomized Study of Motivational Counseling in Preventing Postpartum Smoking Relapse in Pregnant Women Who Quit Smoking During Pregnancy
Prostate
IMPACT Study: Identification of Men With a Genetic Predisposition to ProstAte Cancer
Shared Decision Making: Prostate Cancer Screening
Community Interventions in Non-Medical Settings to Increase Informed Decision Making for Prostate Cancer Screening
Phase II Study of Prostate Cancer Screening and Dietary Heterocyclic Amine Exposure in African American Men
Randomized Study of Fish Oil Supplements in Preventing Prostate Cancer in Patients With Prostatic Intraepithelial Neoplasia or Who Are at Risk for Developing Prostate Cancer
Effects of ASA on Prostate Tissue
Phase I Randomized Study of Lycopene in Healthy Male Participants
Phase II Randomized Chemoprevention Study of Calcitriol in Patients With High-Grade Prostatic Intraepithelial Neoplasia
Skin
Phase II Randomized Study of Celecoxib as a Chemopreventive Agent Inhibiting UV-Induced Erythema and Biomarkers of Cutaneous Carcinogenesis Participants With FitzpatrickType I-IV Skin (sponsored by the Herbert J. Irving Cancer Center and the NCI)
Study of Clinical, Laboratory, and Epidemiologic Characteristics of Individuals and Families at High Risk for Melanoma
Screening Study of Cancer Risk in Participants Who are Heterozygous Carriers of Xeroderma Pigmentosum Disease Gene Mutations Versus Non-Carrier Blood Relatives or Spouses
Sun Protection for Florida's Children
